Abstract

Attempts at oral transmission of mammary tumour agent by feeding male organs.

Highlights

  • ANTDRRE PEACOCKTHE male mouse harbours the mammary tumour virus in its testes, spermatozoa vesicular glands and fluid (Andervont and Dunn, 1948; Miihlbock, 1950) as well as in other sites

  • Miihlbock (1 952a) suggests that repeated copulation by increasing the mammary agent transmitted by a " high cancer " male to a " low cancer " female eventually leads to a high enough concentration of agent for the mother to transmit it to her young in the milk

  • Vesicular gland.-The males were killed by cervical dislocation, the vesicular gland was rapidly exposed and a fine glass rod was dipped repeatedly into its lumen to collect the secretion which was inserted into the mouths of the young mice

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Summary

ANTDRRE PEACOCK

THE male mouse harbours the mammary tumour virus in its testes, spermatozoa vesicular glands and fluid (Andervont and Dunn, 1948; Miihlbock, 1950) as well as in other sites. Miihlbock (1 952a) suggests that repeated copulation by increasing the mammary agent transmitted by a " high cancer " male to a " low cancer " female eventually leads to a high enough concentration of agent for the mother to transmit it to her young in the milk. He injected extracts of embryos removed from high cancer strain mothers with mammary tumours into 3 to 4 weeks old susceptible mice (Muhlbock, 1952b). In the following experiments it was proposed to test the possibility of contamination by salivary, testicular or vesicular gland secretions

Feeding methods
Experiment I
ANDREE PEACOCK
RESULTS
DISCUSSION
SUMMARY

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