Attaching importance to diagnosis and treatment of peritoneal metastases from colorectal cancer

Abstract

Peritoneal metastasis from colorectal cancer (CRC) are generally considered to be end-stage disease of CRC, which has greatly impacted the prognosis and quality of life of patients. In recent years, cytoreductive surgery and hyperthermic intraoperative intraperitoneal chemotherapy following systemic control has gradually been accepted for the treatment of peritoneal metastasis from CRC. Unfortunately, it has not widely used in clinical practice for the reasons of instruments, experience, surgical complexity, postoperative complications and cost-effectiveness. There is still no sufficient importance attached to CRC with peritoneal metastasis. Researches on the mechanism and treatment of peritoneal metastasis should be encouraged. Screening of high risk patients for early intervention to reduce incidence of peritoneal metastasis, selecting effective regimens and exploring optimal model for patients with other distal metastasis to improve the outcome of patients may be of importance. Key words: Colonic neoplasms; Rectal neoplasms; Peritoneal metastasis, colorectal cancer; Cytoreductive surgery and hyperthermic intraoperative intraperitoneal chemotherapy; Individualized treatment