Attach importance to the study on mechanism of invasion and metastasis of uveal melanoma

Abstract

Uveal melanoma(UM) is the most common primary intraocular malignant tumor in adults,which is tend to metastasize.The mortality of the patients with the metastatic tumor is very high.The mechanism of the UMmetastasis is associated with genes mutation,cytokine,protein expression abnormality and regulation abnormality of signal transduction pathways.Some research about the mechanism of the UM metastasis is carring out to find the early metastatic marker and potential therapeutic target point,so that the tumor can be detected early and prevented.It will be very important for us to increase the survival rate and improve the life quality of UM patients. Key words: Uveal melanoma; Invasion; Metastasis; Survival rate