Abstract

Summary 1. Atropine, though used with impunity in varied conditions, may cause poisoning; it also occurs in wild plants in sufficient amounts to cause poisoning if they are eaten. 2. Poisoning has occurred in adults with doses of less than 1 mg., 12 and fatalities with 2 mg. In children fatalities have been reported from 0.4 mg. 3. Four drops of a 1 per cent solution of atropine contain 2 mg. (1/30 gr.) of the drug. 4. Toxic symptoms: Hot, dry, flushed skin, dilated pupils, nausea, diarrhea, delirium, staggering gait, and coma. 5. Treatment consists of administration of parasympathetic drugs until the mouth is moist, copious lavage of the stomach, cerebral stimulants if coma is present, and catheterization of the bladder. High temperatures should be controlled by alcohol sponges, forced fluids.

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