Atrial extrasystoles associated with hypervitaminosis D3 (clinical case)

Abstract

The article discusses a clinical case of a patient with hypervitaminosis D3. Cholecalciferol intoxication occurred against the background of long-term oral use of vitamin complexes and was manifested by the manifestation of arrhythmic syndrome – frequent atrial extrasystole of the “P on T” type. The probable pathogenetic cause of arrhythmia was a violation of ion homeostasis in the form of hypercalcemia. Calcium imbalance, affecting cardiac conduction and automatism, can provoke cardiac arrhythmias by increasing the dispersion of refractoriness. At the electrophysiological level, the cause of early atrial ectopia is increased trigger activity during a period of relative cardiac refractoriness. Thus, hypervitaminosis D, associated with subclinical hypercalcemia, may have an arrhythmic "mask".