Abstract
Atrazine-Mediated Oxidative Stress Responses and Lipid Peroxidation in the Tissues of Clarias gariepinus
Highlights
The use of synthetic herbicides and pesticides to bring about improved agricultural production has become an acceptable norm and it is practiced globally in contemporary times
Juvenile African catfish, C. gariepinus of the same brood stock were procured from the hatchery of National Institute for Freshwater Fisheries Research (NIFFR), Kainji, Nigeria
In the liver (Table 3) glucose level increased in a concentration-dependent manner
Summary
The use of synthetic herbicides and pesticides to bring about improved agricultural production has become an acceptable norm and it is practiced globally in contemporary times. Worse hit by chemical pollutants are the fish residents of the aquatic ecosystem and quite a number of studies have reported and confirmed their biological and toxicological responses to atrazine Some of these include behavioral [6], toxicological and bioavailability [3, 7], physiological [4] genetic [8] and biochemical [1, 4] responses. Methods: Atrazine toxicity was determined by assessing the responses of glucose, protein, alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), superoxide dismutase (SOD), acetylcholinestarase (AChE) and malondialdehyde (MDA) in blood, gill and liver of fish exposed to both acute (0.00, 28.00, 30.00, 32.00 and 34.00 μg/l) and chronic (0.00, 7.00, 7.50, 8.00 and 8.50 μg/l) concentrations for 96 h and 28 d, respectively.
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