Abstract
Adenosine triphosphatases (ATPases) have been implicated as the energy-transfer agents for the transport of inorganic ions in animal and bacterial cells. Animal cells have a (Na++K+)-ATPase on the plasma membrane (Skou, 1965; Hokin and Dahl, 1972), a (Ca2+)-ATPase on the sarcoplasmic reticulum of muscle cells (Martonosi, 1972), and an ion translocating ATPase on the inner mitochondrial membrane (Cereijo-Santalo, 1970). Bacterial cells have a (K+)-ATPase on their plasma membrane (Abrams et al., 1972; Rothstein, 1972). The evidence is now convincing that each of these ATPases functions as an energy transducer in the transport of ions across membranes.
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