Abstract
Atorvastatin protects renal function in the rat with acute unilateral ureteral obstruction
Highlights
Editorial Comment This group of investigators has been studying the effects of growth hormone for more than 10 years
They have demonstrated previously that growth hormone likely mediates penile erection through its stimulating effect on the cGMP pathway in human cavernous smooth muscle. They compared the in vivo serum profiles of growth hormone in the systemic and cavernous blood samples obtained from healthy volunteers were compared to the serum profiles of patients with erectile dysfunction
Previous studies have demonstrated that treatment with statins attenuated renal structural damages in rodents with chronic ureteral obstruction (UUO)
Summary
Editorial Comment This group of investigators has been studying the effects of growth hormone for more than 10 years. They have demonstrated previously that growth hormone likely mediates penile erection through its stimulating effect on the cGMP pathway in human cavernous smooth muscle. Systemic growth hormone serum levels significantly increased during penile tumescence, followed by a transient decline from tumescence to rigidity and detumescence.
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