Abstract
Atomic absorption spectrometry provides a convenient and versatile instrumental method for measurements of trace metals in biological materials. An important innovation is the recent development of nonflame atomization devices, which have substantially improved the analytical sensitivity of atomic absorption spectrometry. Applications of atomic absorption spectrometry of trace metals in clinical pathology have been expanded by the recent recognition of clinical syndromes associated with copper and zinc deficiency, and the discovery of abnormalities of chromium and nickel metabolism in various human diseases.
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