Atherogenic Index Profile on Ischemic Stroke Patients at Neurology Department, Dr. Soetomo Surabaya: A Retrospective Study

Abstract

Stroke was associated with morbidity and mortality in the world. Lipid index discovered through lipid profile tests may be used as a predictor in vascular diseases. To increase the prediction value of lipid profile to stroke outcome, several lipoprotein ratios, called atherogenic index, were still being researched. Atherogenic indexes included Atherogenic index of plasma, Castelli Risk Index I and II, atherogenic coefficient, and non-high density lipoprotein cholesterol. The aim of this study is to find atherogenic index profile as a marker for atherogenicity on acute ischemic stroke patients at Neurology Department Dr. Soetomo hospital from January-September 2019. This is a retrospective descriptive of 65 patients on stroke registry. Data collected including low and high AIP level on 19, 46 patients, respectively; low CRI I on 22 patients and high CRI I on 43 patients; low CRI II from 31 patients and high CRI II from 34 patients; low and high AC on 9 and 56 patients, respectively; also, low NHC on 21 patients and high NHC on 44 patients. Poor outcome on outpatient was identified in 30 patients (NIHSS >7). This study indicates most ischemic stroke patients have high atherogenic index level. Analysis on the differences between lipid index and NIHSS poor outcome revealed AC and NHC level were significant with p = 0,031, CI 8,593 (1,007 – 73,319) and p = 0,01, CI 9,529 (2,435 – 37,3), respectively. Keywords: atherogenic index, ischemic stroke, NIHSS.