Abstract
We consider a class of nonlinear models associated with erythropoiesis and establish a global asymptotic stability result for the trivial steady state, which extends essentially some previous results. Moreover, we give numerical simulations to illustrate this theoretical result.
Highlights
1 Introduction Erythropoiesis is the process by which red blood cells are formed
CD + progenitors are isolated from adult peripheral blood or cord blood and grown in liquid medium in fibronectin-coated wells. These progenitor stem cells constitute approximately . % of nucleated cells in the bone marrow, only about % of which are in cycle at any one time
Mature erythroblasts are smaller with tightly compacted nuclei which are expelled as the cells become reticulocytes
Summary
Erythropoiesis is the process by which red blood cells (erythrocytes) are formed. It is a complex process, stimulated by decreased O in circulation. This process (erythropoiesis) is based upon the differentiation of the hematopoietic stem cells. For more information about erythropoiesis and the differentiation of the hematopoietic stem cells, we refer the reader to [ – ] and references therein.
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