Abstract
BACKGROUND: a case report of 17year old male with acute risperidone + trihexyphenidyl poisoning with transient sinoatrial block without any CNS or neuromuscular complications. CONCLUSION: Risperidone does possess cardiotoxicity as of cardiac conduction abnormalities mainly affecting SA 1 and AV nodes rather than prolongation of QT interval without causing hypotension or myocardial injury . Such a nonlethal conduction aberrancy was observed at a dose of 75mg risperidone was only transient and reversed physiologically without any additional treatment. Further protection from extrapyramidal symptoms was offered by combined drug trihexyphenidyl at cost of sedation.
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