Abstract

PurposeThere is increasing evidence indicating that considerable fractions of cases of SARS-CoV-2 infection are asymptomatic. We traced three asymptomatic clusters to investigate the infectivity of subclinical cases of coronavirus disease 2019 (COVID-19).Patients and MethodsThree medical staff who were asymptomatic were diagnosed with coronavirus disease 2019 by serological tests. Their close contacts were systematically evaluated based on COVID-19-related symptoms, nucleic acid tests, serological tests, and chest computed tomography (CT) as needed to determine if they were infected by SARS-CoV-2.ResultsNone of the staff’s close contacts, including 10 family members, were infected by the indexes, even though no protective measures were taken.ConclusionThe infectivity of asymptomatic subclinical infection patients of coronavirus disease 2019 seems to be low.

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