Abstract
To ascertain whether women at high risk for human immunodeficiency virus (HIV) seropos-itivity are identifiable, individual patient information was collected and numerically linked with the results of anonymous HIV antibody testing. Each patient's risk profile, incorporating routinely available historical and laboratory risk factor information, was examined. Of 2,510 consecutively delivered mothers, 13 were seropositive (prevalence = 5 per 1,000); of these, 12 (92%) were asymptomatic. Based on risk profiles, all seropositive women had been recognized as belonging to one or more high risk groups. The strongest predictors of seroposittvity were maternal intravenous drug use (IVDU) (adjusted odds ratio, 49.5; 95% confidence interval, 11.7-209.8) and history of sexually transmitted disease (STD) (adjusted odds ratio, 11.6; 95% confidence interval, 3.0-45.1).Infants of seropositive mothers had a greater incidence (P < 0.05) of low birth weight, prematurity, and need for intensive care than those of seronegativ...
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