Abstract
BACKGROUNDPulmonary tuberculosis (TB) is a leading cause of morbidity and mortality, and East Java province is the second largest contributor of co-infection in Indonesia. Asymptomatic helminth infection among pulmonary tuberculosis patients causes another public health problem. Few data relate to helminth infection based on clinical and immunological outcomes of pulmonary TB in highly endemic areas.
 METHODSThis study was designed as a preliminary study and aimed to determine helminth co-infection among TB patients with a macroscopic assessment. This cross-sectional study was conducted in June-August 2017.
 RESULTSAmong 16 treated active TB patients from TB cohort data of Tanakali Kedinding health center found that 56% were stool smear-positive for Trichuris trichiura eggs, but had no clinical symptoms.
 CONCLUSIONWhether or not the helminth infection may have an impact on the diagnosis and treatment of active TB remains to be further investigated. Co-infection could be inhibited by the host immune response and improve the prognosis of TB treatment.
Highlights
Pulmonary tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that has high morbidity and mortality rates
Co-infection could be inhibited by the host immune response and improve the prognosis of TB treatment
Based on the stool direct smear results 9 out of 16 subjects (56.25%) who suffered from pulmonary tuberculosis were positively coinfected with soil-transmitted helminths (STH), which was Trichuris trichiura
Summary
Pulmonary tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that has high morbidity and mortality rates. According to National Health Report data 2016, tuberculosis is still one of the leading causes of high morbidity among all infectious diseases at the health centers and Indonesia was in the third rank among TB burden countries.[2]. People living in slum and squatter areas are usually affected with tuberculosis and intestinal helminth infection, especially co-infection with soil-transmitted helminths. It is well-known that intestinal parasitic infections are one of the neglected tropical infections and one of the most common infections in the world.[3] The occurrence of co-infection of TB and intestinal helminthiasis has become one of the major public health problems in Indonesia. Few data relate to helminth infection based on clinical and immunological outcomes of pulmonary TB in highly endemic areas
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
