Abstract
Colistin is a polymyxin group antibiotic, and colistimethate-sodium is the prodrug form of colistin and is inactive. Colistin is often the last optional drug for nosocomial infections caused by multidrug-resistant gram-negative microorganisms. We present a case of asymptomatic eosinophilia due to systemic colistin therapy. The increasing trend of absolute eosinophil counts appeared with recurrent colistin therapy and decreased when colistin was discontinued. The Naranjo Adverse Drug Reaction Probability Scale score was 7, and this score was classified as 'probable' for this case. Clinicians should consider this drug reaction in a patient with eosinophilia and avoid unnecessary laboratory tests and treatments.
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