Abstract
Asymptomatic diabetes: screening by routine imaging beneficial?
Highlights
For the Netherlands, in 2011 a total of 830,000 individuals (415,900 male, 418,200 female) were known with diabetes mellitus, of whom 90 % with type 2 diabetes
Routine screening for coronary artery disease (CAD) is controversial [6,7,8]. It is not recommended by the American Diabetes Association (ADA), since it does not improve outcomes as long as cardiovascular risk factors are treated
The hypothesis was that CAD screening with coronary computed tomography angiography (CCTA) in patients with diabetes mellitus and no known CAD would reduce cardiovascular outcomes compared with routine management, i.e. standard national guidelines–based optimal diabetes care
Summary
For the Netherlands, in 2011 a total of 830,000 individuals (415,900 male, 418,200 female) were known with diabetes mellitus, of whom 90 % with type 2 diabetes. A total of 281 million men and 317 million women worldwide with diabetes died in 2011, most from cardiovascular disease in particular coronary artery disease (CAD). Silent myocardial ischaemia affects 20–35 % of diabetes patients who have additional risk factors, and 35–70 % of patients with silent ischaemia have significant coronary stenosis at coronary arteriography.
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