Asymptomatic catheter related Rhizobium radiobacter infection in a haploidentical hemapoetic stem cell recipient

Funda Erol Çipe,Figen Doğu,Aydan İkincioğulları,Derya Aysev,Deniz Sucuoğlu

doi:10.3855/jidc.1009

Funda Erol Çipe, Figen Doğu + Show 3 more

Open Access

https://doi.org/10.3855/jidc.1009

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Abstract

Catheter related infections are reported as one of the most common source of nosocomial infections. Rhizobium radibacter infections are generally manifested by fever and leukocytosis. Here, a 14 months-old girl diagnosed as T (-) B (-) NK (+) severe combined immunodeficiency (SCID) is presented. She had received repeated (x3) unconditioned haploidentical hematopoetic stem cell transplantations. During the follow-up, she has been arised an asymptomatic infection with R. Radiobacter, which was isolated from central venous catheter and peripheral blood while she was clinically stable, free of symptoms, fever or leukocytosis. She was treated successfully with cefepime and amikacin and did not require catheter removal. So, it is once more clear that the blood cultures should be obtained on regular basis from all patients with an intravascular device, even they were asymptomatic.

Highlights

Central venous catheters (CVC) are used for patients who require long-lasting procedures such as hematopoetic stem cell transplantation (HSCT)
We report an asymptomatic CVCrelated bacteremia caused by an R. radiobacter strain in a 14-month-old girl who had undergone repeated HSCTs due to severe combined immunodeficiency (SCID)
Our patient came to the hospital for a routine control visit and to receive prophylactic intravenous immunoglobulin (IVIG) infusion; soil exposure or recent hospitalization history are not viable as possible sources of the microorganism

Summary

Introduction

Introduction Central venous catheters (CVC) are used for patients who require long-lasting procedures such as hematopoetic stem cell transplantation (HSCT). We report an asymptomatic CVCrelated bacteremia caused by an R. radiobacter strain in a 14-month-old girl who had undergone repeated HSCTs due to severe combined immunodeficiency (SCID). Cipe et al – Rhizobium radiobacter infection in an HSCT Patient days.

Results

Conclusion