Asymmetric version of P-S to P-C [1,3]-sigmatropic rearrangement in the ferrocene series

Abstract

The synthesis of new 2-sulfanylferrocenylphosphonates and derivatives has been achieved through a P-S to P-C [1,3]-sigmatropic rearrangement. The asymmetric version of this reaction has been successfully performed starting from a ferrocenylphosphorodiamidothioate and afforded, as a single diastereoisomer, enantiomerically pure planar chiral ortho-thio-substituted ferrocenyl phosphorodiamidate.