Asymmetric Transfer Hydrogenation of Aromatic Ketones Catalyzed by SBA-15 Supported Ir(I) Complex Under Mild Conditions

Abstract

A heterogeneous catalyst of Ir(I)-9-amino epi-cinchonine complex immobilized on the surface of mesoporous SBA-15 was firstly synthesized and used in the asymmetric transfer hydrogenation of aromatic ketones. Enhanced enantioselectivity compared with homogeneous catalyst was obtained at room temperature. Furthermore, the heterogeneous system with very low leaching of iridium can be easily regenerated. Enhanced enantioselectivities have been achieved in heterogeneous asymmetric transfer hydrogenation of aromatic ketones using a mesoporous SBA-15 supported Ir(I)-9-amino epi-cinchonine complex; moreover, the heterogeneous system with very low leaching of iridium can be easily regenerated.