Abstract

The asymmetric synthesis of (S)-malic esters was carried out by reduction of β-ketosulfoxides derived from β-ketoesters as well as the transformation of (S)-malic esters into syn and anti-1,2-diols via the reduction of β-keto-γ-alkoxy-sulfoxides. An application to the preparation of 2-deoxy-D-ribose and 2-deoxy-L-xylose derivatives is described.

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