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Abstract
Chiral alcohols possessing an asymmetric 2-oxazoline ring were synthesized as new chiral Brønsted acids from tetrahydro-2-furoic acid and (1S,2R)-2-amino-1,2-diphenylethanol. These alcohols were superior to (S,S)- or (R,R)-imide reported previously as a chiral proton source for enantioselective protonation of lithium enolate of an alanine derivative.
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