Abstract
An organocatalytic direct asymmetric Michael addition of bis(phenylthio)propan-2-one to differently substituted aromatic nitroalkenes is described. Takemoto’s thiourea catalyst efficiently promoted this reaction under mild conditions producing the desired products in synthetically useful yields and diastereo- and enantioselectivities. A single crystallization step could further improve the enantiomeric excess up to 98 %.
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