Abstract
A convenient express procedure for the preparation of methyl (Z)-2-acetamido-3-(3,4-dimethoxyphenyl)acrylate was developed. Asymmetric hydrogenation of this substrate in the presence of rhodium catalysts involving synthetically available amidophosphite ligands was carried out, which is characterized by high enantioselectivity (to 99.5% ee) and complete conversion. An approach to the selective formation of cationic complexes containing two ligands of different nature in one coordination sphere of rhodium was suggested.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
