Asymmetric Friedel–Crafts reaction of N-heterocycles and nitroalkenes catalyzed by imidazoline–aminophenol–Cu complex

Abstract

Catalytic asymmetric Friedel-Crafts reaction of pyrrole with nitroalkenes was smoothly catalyzed by newly synthesized nitro-substituted imidazoline-aminophenol (1b)-Cu complex to give the adduct with up to 92% ee.