Abstract
Even though microfluidics has been successfully used in minimizing complicated and onerous processes, the pumping and tubing systems used with it are yet undeveloped and need immediate development. The present study developed a fluttering bar-driven micropump, mounted on a polydimethylsiloxane microfluidic system. The pump consists of a rectangular ferromagnetic bar and a fan-shaped chamber with an inlet and outlet. Through various experiments, the net flow was examined as a function of chamber shape, inlet and outlet channel location, rotating center of the magnet, and rotational speed. Using high-speed camera and image analysis, the net flow was found to be generated by the fluid inertia associated with the varying reciprocating speeds of the bar inside the fan-shaped chamber. Depending on the locations of the inlet and outlet, the cycle time taken to circulate the loop was significantly reduced from 200 to 4 s. The flow rate of the micropump ranges from 48–225 μl/min, which is proportional to the rotational speed of the magnet (150–3000 rpm). Using a fluttering bar-driven inertial micropump, the microfluidic system not only provides improved mixing, but also eliminates certain problems associated with external tubing and connection.
Highlights
Lab-on-a-chip (LOC) technology has been significantly developed and utilized in diverse applications, including biomedical, fine chemistry, and precision medicine
The present study developed a fluttering bar-driven micropump, mounted on a polydimethylsiloxane microfluidic system
The pump consists of a rectangular ferromagnetic bar and a fan-shaped chamber with an inlet and outlet
Summary
Lab-on-a-chip (LOC) technology has been significantly developed and utilized in diverse applications, including biomedical, fine chemistry, and precision medicine. Even for such a successful miniaturization, microfluidic systems have suffered from complex plumbing,[1] fluidic routing,[2] and difficulties with input/output pumps.[3] The main cause of these problems is the use of external pumps, which are still the most commonly utilized for LOCs.[4]. Power was introduced[13,14] and further developed for a point-of-care immunodiagnostic assay.[15]. These sophisticated pumps have not been widely used in LOC because of their limitations such as maximum flow rate and long operating time
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