Abstract
A reaction with organolithium compounds and the chiral amine (—)-sparteine deprotonates carbamates such as 1 in the α-position forming chiral lithio compounds 2, as shown by D. Hoppe et al. [Eq. (a)]. These react with high stereoselectivity with a variety of electrophiles to yield nonracemic, chiral compounds (see also the communication on p. 1505ff). R1 = alkenyl, R2 = C(O)NiPr2, R3 = nBuLi.
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