Abstract

AbstractSteroids have long played a vital role in organic synthesis because of their unique structural motif and associated biological properties. In recent years, asymmetric synthesis has emerged as a powerful tool for assembling the tetracyclic framework with high levels of molecular diversity. This review summarizes the latest developments in the enantioselective syntheses of both natural and synthetic steroids incorporating the carbocyclic skeleton. The approaches to the synthesis of steroids and related molecules are based primarily on the use of chiral starting materials, the employment of reagent‐controlled asymmetric induction assisted by chiral complexes, chiral Lewis acids or organocatalysts, or the utilisation of chiral auxiliaries.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.