Year-end Sale % OFF 
Abstract
The effects of nitrendipine on stress-induced acute gastric lesions were investigated in rats. Intraperitoneally injected nitrendipine (8, 16, or 32 mg/kg) given 30 min before stress, dose-dependently prevented gastric glandular ulceration. The anti-ulcer effects of nitrendipine were not reversible by indometacin or dexamethasone. These results suggest that calcium is important in gastric pathophysiology and that the proof of gastroprotective effects of calcium channel blockers is of great value in the development of new and improved therapies for treatment and prevention of gastric ulcers in humans.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
