Asthme et reflux gastro-œsophagien. Où en est-on ?

Abstract

Asthma and gastroesophageal reflux disease (GERD) are two common diseases, making it possible that a particular patient will be affected by both diseases at the same time. In fact, the incidence of GERD is much more frequent in asthmatics than in the general population. GERD is usually considered to be a potential trigger for unstable asthma, but this hypothesis is based more on pathophysiological reasoning and numerous experimental studies than on clinical data. Recently, several authors have proposed clinical trials of anti-reflux therapy in patients with unstable asthma who have no digestive symptoms. However, the results of recent controlled studies with large numbers of patients question this proposal.