Abstract

Acute respiratory infections have been established as the principal cause of disease in the Mexican population from 2000 to 2018; however, even when these diseases may aggravate asthma, there is a lack of epidemiologic evidence on the health outcomes when both conditions coexist. Learning about the asthma hospitalizations trends will help us identify monthly variation of hospitalizations, vulnerable groups, needed services, and improvements in therapeutics and prevention. This study aims to analyze the variation in asthma hospitalizations and mortality during the 2010–2018 period in Mexico. Data were obtained from the General Board of Health Information (DGIS) Open Access datasets, which were analyzed taking hospital discharges and hospital deaths recorded from 2010 to 2018 from all public hospitals nationwide. The binomial logistic regression analyses were performed to determine the association between patient ages, hospitalization month, and mortality. The death rate from asthma in Mexico decreased between 2010 and 2018. Still, the hospital mortality rate shows recent improvement; however, prognosis of hospitalized patients depends on their age, accurate diagnosis, length of hospital stay and occurrence of nosocomial infection.

Highlights

  • Asthma is a chronic bronchial disorder associated with obstruction of the airways, characterized by recurrent episodes of paroxysmal dyspnea, and derived from a spasmodic contraction of the bronchi.Wheezing, chest tightness, and cough are some classic symptoms of the disease due to airway hyperresponsiveness, but when these symptoms aggravate, dyspnea may become fatal if not properly controlled [1,2]

  • 2010and and2018, 2018, asthma was primary of hospitalizations in of a 87,726 total ofpatients admitted at public hospitals, and it was the primary cause of death in

  • We have provided an overview of asthma-related mortality and its clinical course outcomes of hospitalizations at public institutions in Mexico between 2010 and 2018

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Summary

Introduction

Asthma is a chronic bronchial disorder associated with obstruction of the airways, characterized by recurrent episodes of paroxysmal dyspnea, and derived from a spasmodic contraction of the bronchi.Wheezing, chest tightness, and cough are some classic symptoms of the disease due to airway hyperresponsiveness, but when these symptoms aggravate, dyspnea may become fatal if not properly controlled [1,2]. Asthma is a chronic bronchial disorder associated with obstruction of the airways, characterized by recurrent episodes of paroxysmal dyspnea, and derived from a spasmodic contraction of the bronchi. According to global research in 2014, approximately 300 million people, or 4.3% of the world population have asthma [3]. Due to differences regarding diagnostic protocols access to medical care, it is difficult to establish a global prevalence of asthma. One of the most important studies that have provided an overview of the disease is the International Study on Asthma and Allergies in Childhood (ISAAC) [4,5]. ISAAC showed that countries with the highest prevalence of asthma in children aged six and seven are Australia, Costa Rica, and New Zealand (26.5 to 27.1%).

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