Abstract
In the article results of own researches concerning peculiarities of the course of asthenic syndrome in school-aged children with chronic hepatitis B, C and mixed forms are provided. It is established that chronic hepatitis C as well as a mixed hepatitis are accompanied by more evident symptoms of deadaptation and somatogenic asthenia than hepatitis B in which psychogenic manifestations prevailed. The degree of endogenous intoxication was also higher at hepatitis C.
Highlights
At least 360 million people worldwide are chronically infected by the hepatitis B virus
It is well known that the U.S Food and Drug Administration approved only five medications for treatment of children with chronic hepatitis B: interferon, lamivudine, adefovir, entecavir and, recently, tenofovir
In 70.0 % of children there was confirmed the diagnosis of viral hepatitis B, in 28.0 % of patients — hepatitis С respectively
Summary
At least 360 million people worldwide are chronically infected by the hepatitis B virus. It is well known that the U.S Food and Drug Administration approved only five medications for treatment of children with chronic hepatitis B: interferon- , lamivudine, adefovir, entecavir and, recently, tenofovir. The issue of asthenia development at a number of chromic somatic and infectious diseases in childhood, as well as therapy of violations of psychoemotional status, remains understudied. Asthenic syndrome as a manifestation of a number of somatic, infectious and psychoneurological diseases can be often found in a pediatrician’s practice [4]. The situation becomes more complicated by creation of an unfavourable clinic-and-paraclinic background on which other pathologic symptom complexes and diseases can be «thread» [2, 3]
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