Associative structure of conditioned inhibition produced by inhibitory perceptual learning treatment.

Abstract

Exposure to a set of complex stimuli yields an enhanced ability to discriminate between these stimuli. In previous experimental studies, two distinguishable stimuli, X and A, were each repeatedly paired with a common Stimulus B to create compound Stimuli XB and AB. Prior evidence suggests that unique Features X and A form mutually inhibitory associations. This was evidenced by pairing Feature A with a biologically relevant stimulus (i.e., an unconditioned stimulus [US]) and observing that Stimulus X alone later serves to inhibit anticipatory behaviors for that US. These observations may reflect the mutually inhibitory nature of the two Features X and A. However, by assessing the influence of X on behavior that anticipates the US rather than Feature A, these experiments tested inhibition only indirectly. In the present experiments, a more direct measure of inhibition is proposed and tested with rats. We found evidence of retardation and negative summation of associations between unique Features X and A in their capacity to serve as competing cues during overshadowing treatments. Stimulus X was less susceptible to overshadowing by A (which is indicative of retardation of the establishment of an X-A within-compound association) and was able to suppress overshadowing by A of another stimulus (Y) when X was presented with Y at test (which is indicative of negative summation of the representation of A by X). Thus, XB/AB trials were seen to establish an inhibitory relationship between X and A.