Associations of Health, Lifestyle and Psycho-Social Factors With Sleep Quality During the Early Phase of the COVID-19 Pandemic: A Focus on UK Older Adults Deemed Clinically Extremely Vulnerable

Abstract

Background: Sleep quality is crucial for health and wellbeing in all ages and sleep abnormalities may contribute to multimorbidity in older adults. The impact of pandemic-related disruptions to sleep quality in older adults, particularly those deemed “clinically extremely vulnerable” to COVID-19-related complications (COVID-19CEV) remains unknown.Methods: In this cross-sectional study, conducted during the first UK lockdown (April- June 2020), we surveyed 5558 adults aged 50 years and over (of whom 523 met criteria for COVID-19CEV) with assessments of sleep quality, health/medical, lifestyle, psychosocial and sociodemographic factors. We identified associations between these factors and sleep quality and explored interactions of COVID-19CEV status with factors significantly associated with sleep quality to identify potential moderating variables.Findings: 37% of participants reported poor sleep quality which was associated with younger age, female sex and multimorbidity. Significant associations with poor sleep included, among health/medical factors: COVID-19CEV status, higher BMI, arthritis, pulmonary disease, and mental health disorders; .and the following lifestyle and psychosocial factors: living alone, higher alcohol consumption, an unhealthy diet and higher depressive and anxiety symptoms. r Moderators of the COVID-19CEV status - sleep quality relationship included marital status, loneliness, anxiety and diet. Within this subgroup, less anxious and less lonely males, as well as females with healthier diets, reported better sleep quality. Interpretation: Sleep quality in older adults was compromised during the sudden unprecedented nation-wide lockdown due to distinct health/medical, lifestyle and psychosocial factors. Male and female older adults with COVID-19CEV status may benefit from targeted mental health and dietary interventions, respectively. Results inform tailored interventions and policy for older adults deemed COVID-19CEV. Funding Information: This study was sponsored by Imperial College London and partly funded by the ICHT BRC.Declaration of Interests: Dr. Middleton reports clinical trial grants from Janssen R&D, Novartis and Takeda outside the submitted work. All authors declare no competing interests related to this study.Ethics Approval Statement: Data collected as in this study are anonymized and kept strictlyconfidential in accordance with the UK General Data Protection Regulations (2016). The CCRR study was ethically approved by the Imperial College London Joint Research Compliance Office (20IC5942) and by the Health Research Authority (16/EM/0213).