Abstract
Introduction: This research aims to detect possible associations between the ACTN3 R577X, ACE I/D, BDKRB2 +9/-9 genetic polymorphisms, and selected anaerobic performance indicators among elite and sub-elite fencers. Methods: The sample of participants included a group of 20 fencers (males, age 25.5 ± 6.9 years; height 185.1 ± 5.8; weight 78.3 ± 9.8). We obtained genotype analysis for selected polymorphisms (ACTN3 R577X, ACE I/D, BDKRB2 +9/-9) through buccal swabs. 30-second Wingate test was used for the anaerobic performance where the following variables were monitored: the maximal anaerobic performance – Pmax [W], the anaerobic capacity – AnC [kJ], the total number of revolutions – TR [n], the peak blood lactate concentration – LApeak [mmol·l-1]. Results: Within ACTN3 R577X polymorphism, no differences were found in the observed variables between genotypes. However, ACE I/D heterozygotes reached higher Pmax, AnC, and LApeak values than homozygotes. Furthermore, BDKRB2 +9/-9 polymorphism homozygotes with -9 allele reached higher Pmax and AnC values than homozygotes with +9 allele. No statistical differences were found in all monitored variables between genotypes of monitored polymorphisms. Conclusions: The research findings might serve as another useful piece of knowledge related to the existing statements in the field of genetics, focusing on speed-strength performance problems. It should be highlighted that current studies are only the first steps in helping us better understand the associations between genetic factors and performance in sports.
Highlights
This research aims to detect possible associations between the ACTN3 R577X, ACE I/D, BDKRB2 +9/-9 genetic polymorphisms, and selected anaerobic performance indicators among elite and sub-elite fencers
This study investigates possible associations between the ACTN3 R577X, ACE I/D, BDKRB2 +9/-9 polymorphisms, and the selected variables determined through an anaerobic test WT30
The Hardy-Weinberg equilibrium confirmed the normal distribution of allele frequencies within ACTN3 R577X (p = 0.71), ACE I/D (p = 0.67) and BDKRB2 +9/-9 (p = 0.48)
Summary
This research aims to detect possible associations between the ACTN3 R577X, ACE I/D, BDKRB2 +9/-9 genetic polymorphisms, and selected anaerobic performance indicators among elite and sub-elite fencers. There are studies [7] where the focus is only on speed-strength performance, and the authors address 14 different markers (parts of the genes ACE, ACTN3, AGT, AGTR2, AMPD1, NOS3, PPARA, PPARG, SOD2, TRHR). Petr et al [9] searched for associations between polymorphism PPARA C/G and the performance reached in an anaerobic test among a group of elite ice-hockey players. Authors such as Norman et al [10] or Bouchard and Hoffman [11] contributed to research focused on associations between athletes' anaerobic performance athletes and genetics anaerobic performance. Gene polymorphisms are monitored in vasodilation, metabolism, or muscle fibers' transformation [14]
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have