Abstract

BackgroundAssociations between the frequency of social and intellectual activities and cognitive trajectories are understudied in Chinese middle-aged and older adults. We aimed to examine this association in a nationally representative longitudinal study.MethodsThe China Health and Retirement Longitudinal Study (CHARLS) is a nationally representative sample of Chinese middle-aged and older participants. The frequency of social and intellectual activities was measured at baseline. Interview-based cognitive assessments of orientation and attention, episodic memory, and visuospatial skills and the calculation of combined global scores were assessed every 2 years from 2011 to 2016. Cognitive aging trajectories over time were analyzed using group-based trajectory modeling, and the associations of the trajectory memberships with social and intellectual activities were analyzed using multinomial logistic regression. Odds ratios (OR) and 95% confidence intervals (CI) were reported.ResultsAmong 8204 participants aged 50–75 years at baseline, trajectory analysis identified three longitudinal patterns of cognitive function based on the global cognitive scores: “persistently low trajectory” (n = 1550, 18.9%), “persistently moderate trajectory” (n = 3194, 38.9%), and “persistently high trajectory” (n = 3460, 42.2%). After adjustment for sociodemographic variables, lifestyles, geriatric symptoms, and health conditions, more frequent intellectual activities (OR 0.54, 95% CI 0.38–0.77) and social activities (OR 0.79, 95% CI 0.65–0.95) were both associated with a lower likelihood of being in the “persistently low trajectory” for global cognitive function.ConclusionsThese findings suggested that more frequent social and intellectual activities were associated with more favorable cognitive aging trajectories.

Highlights

  • Cognitive impairment and dementia are the most common geriatric symptoms in elderly individuals aged 60 years and older [1]

  • Estimated cognitive aging trajectories We tested how many trajectories of cognitive function were optimal to explain the heterogeneity in the global cognitive scores in this population (Table 2)

  • After adjusted for all potential confounders, we found that both more social activity score (β = 0.08, z = 6.28, p < 0.001) and intellectual activity score (β = 0.12, z = 7.38, p < 0.001) were associated with better cognitive function over study periods, and frequency of social activity × time interaction (z = − 3.06, p = 0.002) was statistically significant

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Summary

Introduction

Cognitive impairment and dementia are the most common geriatric symptoms in elderly individuals aged 60 years and older [1]. As the global population is aging, the number of individuals with cognitive impairment or dementia has dramatically increased both in China and internationally [2,3,4]. A recent meta-analysis and systematic review reported that an estimated 15% of the older Chinese population suffered from cognitive impairment [5]. A high prevalence of cognitive impairment translates into a very large economic burden [6]. There is no effective treatment for cognitive impairment or dementia [7]. Associations between the frequency of social and intellectual activities and cognitive trajectories are understudied in Chinese middle-aged and older adults. We aimed to examine this association in a nationally representative longitudinal study

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