Abstract
To estimate and test the difference in rates of violent and non-violent crime during medicated and non-medicated methadone treatment episodes. The study involved linkage of population level administrative data (health and justice) for all individuals (n=14 530) in British Columbia, Canada with a history of conviction and who filled a methadone prescription between 1 January 1998 and 31 March 2015. Methadone maintenance treatment was the primary independent variable and was treated as a time-varying exposure. Each participant's follow-up (mean: 8years) was divided into medicated (methadone was dispensed) and non-medicated (methadone was not dispensed) periods with mean durations of 3.3 and 4.6years, respectively. Socio-demographics of participants were examined along with the main outcomes of violent and non-violent offences. During the first 2 years of treatment (≤2.0years), periods in which methadone was dispensed were associated with a 33% lower rate of violent crime [0.67 adjusted hazard ratio (AHR), 95% confidence intervals (CI)=0.59, 0.76] and a 35% lower rate of non-violent crime (0.65 AHR, 95% CI=0.62, 0.69) compared with non-medicated periods. This equates to a risk difference of 3.6 (95% CI=2.6, 4.4) and 37.2 (95% CI=33.0, 40.4) fewer violent and non-violent offences per 100 person-years, respectively. Significant but smaller protective effects of dispensed methadone were observed across longer treatment intervals (2.0 to ≤5.0years, 5.0 to ≤10.0years). Among a cohort of Canadian offenders, rates of violent and non-violent offending were lower during periods when individuals were dispensed methadone compared with periods in which they were not dispensed methadone.
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