Abstract
Methods Retrospective analysis of 2 etanercept trials. Disease activity was calculated at baseline, 3 mo, and 6 mo. Data were analyzed independent of treatment arm. Visits were classified by highest level of pediatric ACR response. EULAR response levels were based on DAS/DAS28 values. Correlation coefficients were calculated between the above measures. Areas under the receiver operating characteristic curve assessed discriminative characteristics of each continuous measure to the pediatric ACR response measures.
Highlights
15th Paediatric Rheumatology European Society (PreS) Congress Wietse Kuis, Patricia Woo, Angelo Ravelli, Hermann Girschick, Michaël Hofer, Johannes Roth, Rotraud K Saurenmann, Alberto Martini, Pavla Dolezova, Janjaap van der Net, Pierre Quartier, Lucy Wedderburn and Jan Scott Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here.
EULAR response levels were based on DAS/DAS28 values
Good correlation was seen between the DAS, DAS28, CDAI, and SDAI and the ACR pediatric measures of response, supporting value for prospective validation in polyJIA
Summary
Associations between continuous measures of disease activity in adult RA and the pediatric ACR response measures: a secondary analysis of JIA data S Ringold2, Y Chon3 and NG Singer*1 Address: 1University Hospitals/Case Medical Center and Rainbow Babies and Children's Hospital, Cleveland, OH, USA, 2Children's Hospital & Regional Medical Center/University of Washington, Seattle, WA, USA and 3Amgen, Inc, Thousand Oaks, CA, USA * Corresponding author from 15th Paediatric Rheumatology European Society (PreS) Congress London, UK.
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