Abstract
BackgroundTo assess the association between cardiorespiratory fitness (CRF) and weight changes in treatment seeking patients with severe obesity who underwent a 1-year intensive lifestyle intervention (ILI) program.MethodsRetrospective cohort study conducted at a tertiary care outpatient rehabilitation center from November 1, 2013 through January 1, 2017. CRF was measured as maximal oxygen consumption during a maximal oxygen uptake (VO2max) test on a treadmill or bicycle at baseline and after 3 months.ResultsA total of 180 patients had a baseline mean (SD) BMI 41.1 (4.8) kg/m2 and CRF of 79.4 (14.9) mL·kg-0.75·min− 1. Patients with a baseline CRF above median achieved a greater 3-month and 1-year weight loss compared with patients with CRF below median; mean (95% CI) 2.5 kg (1.3, 3.8) and 4.0 kg (0.8, 7.2), respectively. In addition, patients with 3-month changes of CRF above median had 4.0 kg (0.9, 7.1) greater weight loss at 1-year follow-up than those below median.ConclusionsAmong patients with severe obesity who underwent a 1-year ILI program, higher baseline CRF was associated with significantly larger weight loss after 3 months and 1 year. In addition, those with higher initial 3-month CRF changes had greater weight loss at 1 year.Trial registrationRetrospectively registered in Regional Committees for Medical and Health Research Ethics (REC) south east September 22, 2016 (2016/1414) and clinicaltials.gov August 13, 2018 (identifier: NCT03593798).
Highlights
To assess the association between cardiorespiratory fitness (CRF) and weight changes in treatment seeking patients with severe obesity who underwent a 1-year intensive lifestyle intervention (ILI) program
To our knowledge, no previous study has addressed the association between CRF and body weight change in patients with severe obesity undergoing an intensive lifestyle intervention (ILI) program
The primary aim of the present study was to investigate the association between CRF and weight loss in treatment seeking patients with severe obesity, who participated in a 1-year ILI program at a tertiary care center
Summary
To assess the association between cardiorespiratory fitness (CRF) and weight changes in treatment seeking patients with severe obesity who underwent a 1-year intensive lifestyle intervention (ILI) program. Each liter of oxygen consumed liberates approximately 5 kcal, dependent upon the intensity of work [9]. This means that at any given relative work intensity, a higher VO2max is accompanied with a higher energy expenditure. To our knowledge, no previous study has addressed the association between CRF and body weight change in patients with severe obesity undergoing an intensive lifestyle intervention (ILI) program. The potentially predictive effect of CRF on weight loss is uncertain
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