Association of Vitamin D with Obesity in Premenstrual Syndrome: A Study of Female Population of Hyderabad, Sindh

Abstract

Introduction/Objectives: The affiliation between decreased vitamin D and obesity is well built up. Females with Premenstrual Syndrome (PMS) are more prone to gain weight. Obese women's low calcifediol levels are impacted by diets and inactive lifestyles.The studyfocused to discover out the relationship between vitamin D and obesity in premenstrual syndrome females. Materials & Methods: Two hundred fifty (250) females between15-45 yearswith a history of PMS were selected from OPD-Gynecology, Liaquat University of Medical&Health Sciences (LUMHS), Jamshoro and Hyderabad in collaboration with Physiology Department LUMHS Jamshoro and samples were analyzed in Diagnostic and Research lab Hyderabad. Information was collected on marital status, vitamin D3 levels, PMS intensity, and BMI. The Chi-square test compared the vitamin D levels with BMI and PMS scores. Results: Mean age of the patients was 29.89±5.206 years. 64.8% of patients were married. 42.8% had normal weight and 40.8%were obese. 35.2% of patients had mild PMS scores and 36.4% had extreme PMS. 61.2% of patients had vitamin D lack with only 4.8% having adequate serum vitamin D levels. 22.8% of normal-weight patients had inadequate serum vitamin D levels. 35.6% of obese patients had vitamin insufficiency in their blood. The relationship between obesity and vitamin D levels was significant (P-value: 0.001). 18.8% of patients who had mild PMS scores had deficient serum vitamin D levels. The relationship between PMS scores and vitamin D levels was remarkable (P-value: 0.001). Conclusion: We found a significant, inverse relationship between vitamin D levels and BMI, showing that losing weight through vitamin D and calcium-enriched diets may result in typical vitamin D levels, and so PMS may be treated. Keywords: Vitamin D (Vit D),Premenstrual Syndrome, body-mass index(BMI)