Association of valvular aortic stenosis with symptomatic peripheral arterial disease in older persons

Abstract

Roberts 1 Roberts W.C The senile cardiac calcification syndrome. Am J Cardiol. 1986; 58: 572-574 Abstract Full Text PDF PubMed Scopus (179) Google Scholar has suggested that aortic cuspal calcium is a form of atherosclerosis. Older patients with valvular aortic stenosis have a higher prevalence of coronary risk factors, 2 Aronow W.S Schwartz K.S Koenigsberg M Correlation of serum lipids, calcium, and phosphorus, diabetes mellitus and history of systemic hypertension with presence or absence of calcified or thickened aortic cusps or root in elderly patients. Am J Cardiol. 1986; 59: 998-999 Abstract Full Text PDF Scopus (162) Google Scholar , 3 Mohler E.R Sheridan M.J Nichols R Harvey W.P Waller B.F Development and progression of aortic valve stenosis atherosclerotic risk factors—a causal relationship? A clinical morphologic study. Clin Cardiol. 1986; 14: 995-999 Crossref Scopus (198) Google Scholar , 4 Mautner G.C Mautner S.L Cannon III, R.O Hunsberger S.A Roberts W.C Clinical factors useful in predicting aortic valve structure in patients >40 years of age with isolated aortic stenosis. Am J Cardiol. 1986; 72: 194-198 Abstract Full Text PDF Scopus (49) Google Scholar , 5 Stewart B.F Siscovick D Lind B.K Gardin J.M Gottdiener J.S Smith V.E Kitzman D.W Otto C.M Cardiovascular Health StudyClinical factors associated with calcific aortic valve disease. J Am Coll Cardiol. 1986; 29: 630-634 Abstract Full Text Full Text PDF Scopus (1536) Google Scholar a higher prevalence of coronary artery disease, 4 Mautner G.C Mautner S.L Cannon III, R.O Hunsberger S.A Roberts W.C Clinical factors useful in predicting aortic valve structure in patients >40 years of age with isolated aortic stenosis. Am J Cardiol. 1986; 72: 194-198 Abstract Full Text PDF Scopus (49) Google Scholar , 6 Mautner G.C Roberts W.C Reported frequency of coronary arterial narrowing by angiogram in patients with valvular aortic stenosis. Am J Cardiol. 1986; 69: 539-540 Google Scholar , 7 Aronow W.S Ahn C Shirani J Kronzon I Comparison of frequency of new coronary events in older persons with mild, moderate, and severe valvular aortic stenosis with those without aortic stenosis. Am J Cardiol. 1986; 81: 647-649 Abstract Full Text Full Text PDF Scopus (37) Google Scholar , 8 Aronow W.S Ahn C Kronzon I Association of mitral annular calcium and of aortic cuspal calcium with coronary artery disease in older patients. Am J Cardiol. 1986; 84: 1084-1085 Abstract Full Text Full Text PDF Scopus (48) Google Scholar and a higher incidence of new coronary events. 7 Aronow W.S Ahn C Shirani J Kronzon I Comparison of frequency of new coronary events in older persons with mild, moderate, and severe valvular aortic stenosis with those without aortic stenosis. Am J Cardiol. 1986; 81: 647-649 Abstract Full Text Full Text PDF Scopus (37) Google Scholar , 9 Shirani J Yousefi J Roberts W.C Major cardiac findings at necropsy in 366 American octogenarians. Am J Cardiol. 1986; 75: 151-156 Abstract Full Text PDF Scopus (45) Google Scholar , 10 Livanainen A.M Lindroos M Tilvis R Heikkila J Kupari M Natural history of aortic valve stenosis of varying severity in the elderly. Am J Cardiol. 1986; 78: 97-101 Abstract Full Text PDF Scopus (141) Google Scholar , 11 Otto C.M Lind B.K Kitzman D.W Gersh B.J Siscovick D.S Cardiovascular Health StudyAssociation of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly. N Engl J Med. 1986; 341: 142-147 Crossref Scopus (1037) Google Scholar Coronary artery disease and peripheral arterial disease (PAD) frequently coexist. 12 Mautner G.C Mautner S.L Roberts W.C Amounts of coronary arterial narrowing by atherosclerotic plaque at necropsy in patients with lower extremity amputation. Am J Cardiol. 1986; 70: 1147-1151 Abstract Full Text PDF Scopus (52) Google Scholar , 13 Aronow W.S Ahn C Prevalence of coexistence of coronary artery disease, peripheral arterial disease, and atherothrombotic brain infarction in men and women ≥62 years of age. Am J Cardiol. 1986; 74: 64-65 Abstract Full Text PDF Scopus (290) Google Scholar , 14 Ness J Aronow W.S Prevalence of coexistence of coronary artery disease, ischemic stroke, and peripheral arterial disease in older persons, mean age 80 years, in an academic hospital-based geriatrics practice. J Am Geriatr Soc. 1986; 47: 1255-1256 Google Scholar We report the association of valvular aortic stenosis with symptomatic PAD in 989 older men and 1,998 older women.