Abstract
To assess the association of systolic blood pressure (SBP) and diastolic blood pressure (DBP) with mortality among older adults in Singapore. Association of SBP and DBP measured in 2009 for 4443 older adults (69.5±7.4years; 60-97years) participating in a nationally representative study with mortality risk through end-December 2015 was assessed using Cox regression. Higher mortality risk was observed at the lower and upper extremes of SBP and DBP. With SBP of 100-119mmHg as the reference, multivariable mortality hazard ratios [HRs (95% confidence interval)] were SBP <100mmHg: 2.41 (1.23-4.72); SBP 160-179mmHg: 1.51 (1.02-2.22); and SBP ≥180mmHg: 1.78 (1.12-2.81). With DBP of 70-79mmHg as the reference, HRs were DBP <50mmHg: 2.41 (1.28-4.54) and DBP ≥110mmHg: 2.16 (1.09-4.31). Management of high blood pressure among older adults will likely reduce their mortality risk. However, the association of excessively low SBP and DBP values with mortality risk needs further evaluation.
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