Association of Stone Chemical Composition with the Stone-free Result and Operative Time Following Percutaneous Nephrolithotomy

Abstract

Background and Objective: The present study aimed to assess the association between stone chemical compositions and Percutaneous Nephrolithotomy (PCNL) outcomes (stone-free result, operative time). Materials and Methods: In this analytical cross-sectional study, the data of 113 patients who underwent PCNL, including stone chemical composition, stone-free result, and operative time, were recorded and analyzed. Results: In univariate analysis, no significant differences were observed between the group with the stone-free result and the group without stone-free result in mean percentages of calcium phosphate, calcium oxalate, uric acid, and the frequency of infectious stones time (P>0.05). Moreover, operative time was not significantly correlated with the percentages of calcium phosphate, calcium oxalate, and uric acid components (P>0.05). In addition, no significant difference was detected between the two groups (with and without infectious stones) in terms of mean operative time (47.00±17.38 vs. 45.99±20.98; P=0.817). In multivariate regression analysis, none of calcium phosphate, calcium oxalate, uric acid, and infectious stone were the predictive factors affecting stone-free result and operative time. Conclusion: As evidenced by the obtained results, the compositions of upper urinary tract stones had no effect on the stone-free result and operative time in PCNL.