Abstract

Introduction: Paraneoplastic syndromes manifesting as non-caseating epithelioid granulomas have been documented in the medical literature since 1917. these can pose a diagnostic and therapeutic dilemma if not identified as associations. case report: We present a case of mucinous adenocarcinoma in the pancreatic head, associated with hilar and mediastinal lymphadenopathy. After a complicated and ultimately terminal progression of disease, post-mortem lymph node biopsy confirmed non-caseating granulomas. conclusion: thus it is prudent to identify such histopathologic changes with lymph node biopsy before further management decisions are made.

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