Year-end Sale % OFF 
Abstract
BackgroundObjective of the study is to assess prevalence and survival among end stage renal disease patients with restless legs syndrome (RLS) within a national database (USRDS).MethodsA case-control, retrospective analysis was performed. Differences in characteristics between the groups, RLS and those with no sleep disorder (NSD), were determined using χ2 tests. Cox proportional hazard regression was used to assess survival between those with RLS and propensity score matched controls.ResultsCases of restless legs syndrome were defined as patients that had received an ICD-9 code of 333.94 at any point during their treatment (n = 372). RLS group demonstrated a significantly higher proportion of patients with major depressive disorder, dysthymic disorder, anxiety, depression, minor depressive disorder, and psychological disorder. The difference between the survival was not statistically significant in those without sleep disorder as compared to those with RLS (HR =1.16±0.14, p = 0.3).ConclusionsTrue prevalence of RLS in dialysis patients can only be estimated if knowledge gap for care providers in diagnosis of RLS is addressed. RLS patients also have increased incidence of certain psychological disorders which needs to be addressed.
Highlights
Objective of the study is to assess prevalence and survival among end stage renal disease patients with restless legs syndrome (RLS) within a national database (USRDS)
The effects of sleep disorders have been well documented, it is worth noting that disrupted sleep can significantly impact quality of life, resulting in depression, psychological consequences, and even reduced socioeconomic status, in the EndStage Renal Disease (ESRD) population
Results from our analyses reveal two interesting findings: 1) there are no significant differences in mortality between patients who are diagnosed with RLS and those with no sleep disorders, and 2) patients with RLS are more likely to have diagnoses of psychological conditions
Summary
Objective of the study is to assess prevalence and survival among end stage renal disease patients with restless legs syndrome (RLS) within a national database (USRDS). A review of several studies suggested that the prevalence of sleep symptoms could be as high as 44% [1]. In this population, sleep disorders most often manifest as obstructive sleep apnea, excessive sleepiness, and restless legs syndrome (RLS)/Willis-Ekbom disease [4,5,6]. In the endstage renal disease population those on hemodialysis, the prevalence of RLS ranges from 6.6% to 62% [9, 20,21,22,23] This wide variability in reported prevalence may be driven by a number of factors, such as the heterogeneity of study populations, a previous lack of standardized diagnosis criteria, and a number of other confounders and comorbidities. The ESRD population tends to experience a high incidence of paresthesia, itching, cramps and peripheral neuropathy, which have likely contributed to such a high reported prevalence
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
