Association of Renal Volume with the Degree of Aortic Contrast Enhancement in Abdominal CT

Natalia S Muto,Tsukasa Sasaki,Kyongtae T Bae,Hiroki Shirato,Tamotsu Kamishima,Satoshi Terae,Khin Khin Tha

doi:10.4236/act.2013.22011

Abstract

To assess the correlation of renal volume measured on CT with aortic contrast enhancement on the hepatic arterial phase of dynamic CT, 64 consecutive patients (34 men, 30 women) were retrospectively examined. Renal volumes were measured on CT. The aortic contrast enhancement was inversely correlated with renal medullary volume (r = -0.52, p 0.0001), and renal cortical volume (r = -0.3, p = 0.02). Renal volume may have inverse correlation with aortic contrast enhancement on the hepatic arterial phase of dynamic CT. This might call for adjustment of contrast material dose based in part on renal volume in the future.

Highlights

Multiphasic computed tomography (CT) of the liver, including the hepatic arterial phase has played a fundamental role in detecting and differentiating hepatic tumors such as hepatocellular carcinoma and metastatic hypervascular tumors [1]
Renal borders were manually delineated using a cursor by an experienced radiology technologist, voxels were counted by the sotware and renal volume calculated (ZioSystem 1000; Zio Software, Tokyo, Japan)
Bland and Altman plot was made for between the manual and the semi-automated method. Anthropometric parameters such as body weight, height, BMI, BSA, as well as eGFR and renal volumes measured by 3 different methods with respective units are shown on Table 1 with range, mean and standard deviation (SD)

Summary

Introduction

Multiphasic computed tomography (CT) of the liver, including the hepatic arterial phase has played a fundamental role in detecting and differentiating hepatic tumors such as hepatocellular carcinoma and metastatic hypervascular tumors [1]. The most important one affecting the magnitude of vascular and parenchymal contrast enhancement is body weight [7,8,9,10,11]. This effect can be best described on the basis of the association of the body weight with the blood volume. In consideration of the other patient related factors affecting the magnitude of vascular and parenchymal contrast enhancement, the kidney may be the organ to be investigated, because it is a highly vascular organ composing an important part of the blood vessel volume of the body [13].

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Conclusion