Association of Rapid Eye Movement Sleep (REM) Dominant Obstructive Sleep Apnea (OSA)(REM-OSA) Versus Non-REM Sleep Dominant OSA (non-REM OSA) and Suicidal Ideation in Posttraumatic Stress Disorder (PTSD)

Madhulika Gupta

doi:10.1016/j.biopsych.2020.02.383

Association of Rapid Eye Movement Sleep (REM) Dominant Obstructive Sleep Apnea (OSA)(REM-OSA) Versus Non-REM Sleep Dominant OSA (non-REM OSA) and Suicidal Ideation in Posttraumatic Stress Disorder (PTSD)

Madhulika Gupta

https://doi.org/10.1016/j.biopsych.2020.02.383

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Journal: Biological Psychiatry

Publication Date: May 1, 2020

Affiliation: Western University

#Obstructive Sleep Apnea #Suicidal Ideation + Show 8 more

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Abstract

Obstructive sleep apnea (OSA) severity in PTSD correlates directly to suicidal ideation (SI), with depression as a mediator. OSA severity varies with sleep stages as the ventilatory control system sensitivity (loop gain) is significantly lower (and ventilatory control more stable) during REM versus non-REM sleep. This study examined the association of OSA and SI in PTSD patients with REM-sleep dominant OSA (REM-OSA) versus non-REM sleep dominant OSA (non-REM OSA).

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