Abstract
Primary biliary cirrhosis is an autoimmune disorder affecting exclusively liver. There has been association of this autoimmune disease with various other neurological counterparts, but Opsoclonus-Myoclonus Syndrome in conjunction with primary biliary cirrhosis is unreported yet. Opsoclonus-Myoclonus Syndrome is a disorder of eye movement with an ill-defined etiology. It may be idiopathic or present as a paraneoplastic manifestation with a low response to therapeutic modalities. We present a case of primary biliary cirrhosis that developed Opsoclonus-Myoclonus Syndrome during an exaggeration of disease process which responded well to intravenous corticosteroids. Knowledge of association of Primary biliary cirrhosis with Opsoclonus-Myoclonus Syndrome and its good response to treatment in this setting will help in reducing morbidity in similar situations. Key Words: Primary biliary cirrhosis; Opsoclonus-Myoclonus Syndrome DOI: http://dx.doi.org/10.3126/ajms.v2i2.3536 Asian Journal of Medical Sciences 2 (2011) 110-112
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