Abstract

This review evaluated the association of place of residence (urban/rural) and under-five mortality in middle- and low-income countries. Both English and Spanish language studies conducted during the Millennium Development Goal (MDG) period (1990 to 2015) were reviewed. Twenty-six cross-sectional studies, all in the English language, were selected for further review. Published data were used for this analysis. A funnel plot was produced to ascertain the presence of publication bias. The combined relative risk for under-five mortality was estimated using a random-effects model and a meta-regression was conducted on 15 of the 26 studies. The studies had a combined effect size of 1.47 (95% confidence interval, 1.27–1.67). The results of the meta-regression showed a positive association between the relative risk and the percentage of the rural population for the various regions/countries. The coefficient for the variable rural population percentage was 0.007, indicating that for every one percent increase in the rural population percentage, there was a 0.007 increase in the relative risk for under-five mortality. However, this was not significant (p-value = 0.3). Rural disadvantage persists in middle- and low-income countries. This is important to evaluate policies and programmes designed to remove the gap in under-five mortality rates between urban and rural areas.

Highlights

  • Under-five mortality (U5M) is defined as a child dying between birth and their fifth birthday.In 2015, 16,000 children under the age of five died every day, approximating 5.9 million child deaths for the year [1]

  • When the results from 15 studies were combined, the findings were broadly similar for U5M being higher for rural areas than urban areas

  • Many studies indicated that inequalities decreased between urban and rural place of residence [20,25,27,28,38], but some indicated a widening of the gap [24,26]

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Summary

Introduction

Under-five mortality (U5M) is defined as a child dying between birth and their fifth birthday.In 2015, 16,000 children under the age of five died every day, approximating 5.9 million child deaths for the year [1]. The global U5M at the beginning of the Millennium Development Goals (MDGs) era was 91 per 1000 live births in 1990. This reduced by 53% to 43 per 1000 live births in 2015 [2]. Despite this decrease, many countries did not achieve MDG4, which had set the target of reducing U5M by two-thirds between 1990 and 2015. Of particular interest to the present study, are SDGs 3 and 10, which aim to reduce inequalities within and among countries, ensure healthy lives and promote well-being for all ages [3]. Since the 1950s, Children 2018, 5, 51; doi:10.3390/children5040051 www.mdpi.com/journal/children

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