Abstract
Atopic dermatitis (AD) is a widely prevalent skin disease that affects both children and adults. The aim of the study was to assess the association of perceived stress (single-item, self-reported) with AD (self-reported) in a sample of Korean adults using a cross-sectional research design. A cross-sectional study was conducted using data from 33,018 adults aged 20 years and older collected in the 2007–2012 Korea National Health and Nutrition Examination Surveys (KNHANES). An increased level of self-reported stress was positively associated with an increased prevalence of AD in Korean adults (p for trend <0.001). After adjusting for covariates, the odds ratios (ORs) of AD among participants reporting high and very high levels of stress were 1.81 (95% confidence interval (CI): 1.22, 2.67) and 2.17 (95% CI: 1.38, 3.42), respectively, compared with those who reported low levels of stress. This study found a statistically significant association between perceived stress and AD among Korean adults.
Highlights
Atopic dermatitis (AD), a chronic inflammatory skin disease characterized by eczematous lesions and intense itching, is a global public health concern in children and in adults [1,2,3]
The goal of this study was to determine the association between perceived stress and AD in Korean adults by using data obtained from the 2007–2012 Korea National Health and Nutrition Examination Survey (KNHANES), a nationally representative survey conducted in the Republic of Korea
Model 3: adjusted for sex, age, BMI, education, income, cigarette smoking, and alcohol consumption. This nationwide population-based study of Korean adults found that 1.8% of participants had AD, which is quite similar to the results of a recent study showing a 1.88% of AD prevalence in Korean adults [21]
Summary
Atopic dermatitis (AD), a chronic inflammatory skin disease characterized by eczematous lesions and intense itching, is a global public health concern in children and in adults [1,2,3]. AD is caused by a genetic predisposition and environmental factors, including null mutations in filaggrin (FLG), climate, urban living, and diet [4,5]. AD may be associated with psychological problems, such as anxiety, depression, sleep disorders, and personality disorders [6,7]. Of the many factors related to AD, psychological stress is thought to be important [6,8]. Numerous studies have demonstrated that psychological stress has a significant impact on skin inflammation [9]
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More From: International Journal of Environmental Research and Public Health
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